New methods to improve super-resolution imaging techniques give a sharper view inside cells
New methods to improve super-resolution imaging techniques are giving biologists a clearer and more complete view of the inner workings of living cells. Read more at https://phys.org/news/2023-01-methods...
In this video: A new paper in Nature Biotechnology from the Shroff Lab details two practical ways to improve the axial, or z, resolution of 3D structured illumination microscopy, a technique to see inside living cells. In one method, a mirror is added to the microscope to create an additional beam of light, changing the interference pattern, and enabling finer, sharper resolution along the z axis. (video 1). The second method, which uses deep learning, blurs the sharp x and y axes to look like the blurry z axis and then trains a neural network to reverse these blurry images. The network then uses that information to un-blur the z axis. (video 2).
Video Credit: Li et al.
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In this video: A new paper in Nature Biotechnology from the Shroff Lab details two practical ways to improve the axial, or z, resolution of 3D structured illumination microscopy, a technique to see inside living cells. In one method, a mirror is added to the microscope to create an additional beam of light, changing the interference pattern, and enabling finer, sharper resolution along the z axis. (video 1). The second method, which uses deep learning, blurs the sharp x and y axes to look like the blurry z axis and then trains a neural network to reverse these blurry images. The network then uses that information to un-blur the z axis. (video 2).
Video Credit: Li et al.
Subscribe: science-x-network
Join Science X channel to support our mission:
science-x-network
Thank you for helping our YouTube channel reach new heights! Hitting subscribe aids us in our mission to bring you the latest and greatest research news in science, medicine and technology.
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