Streptococcus mutans

Air to air
Air to air
A facultatively anaerobic, gram-positive coccus commonly found in the human oral cavity and is a significant contributor to dent ...
A facultatively anaerobic, gram-positive coccus commonly found in the human oral cavity and is a significant contributor to dental caries (tooth decay).
It is most prevalent on the pits and fissures and fewer on the buccal surface.
It can coexist with Streptococcus sobrinus in the mouth.

Dental caries is a dental biofilm-related oral disease associated with increased consumption of dietary sugar and fermentable carbohydrates. When dental biofilms remain on tooth surfaces, along with frequent exposure to sugars, acidogenic bacteria (members of dental biofilms) will metabolize the sugars to organic acids. Persistence of this acidic condition encourages the proliferation of acidogenic and aciduric bacteria such as Streptococcus mutans, as a result of their ability to survive at a low-pH environment. The low-pH environment in the biofilm matrix erodes the surface of the teeth and causes the dental caries.

(Symbiotic relationship in dental caries)
Bacterial-fungal co-coaggregation can help to increase the cariogenic potential, for example, its symbiotic relationship with Candida albicans leads to increased glucan production and increased biofilm formation. Candida albicans stimulates the formation of Streptococcus mutans microcolonies.

(Comparisons in cardiovascular diseases)
• Streptococcus mutans: Associated with bacteraemia and infective endocarditis (subacute cases). It can be found in extirpated heart valve tissues, as well as in atheromatous plaques.
• Streptococcus sanguinis: A normal inhabitant of the healthy human mouth where it is particularly found in dental plaque, where it modifies the environment to make it less hospitable for Streptococcus mutans and so on. Associated with infective endocarditis.

Cf. farnesol

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